Dr Patrick D' Silva
Professor
| Biochemistry
Indian Institute of Science, Bangalore
Karnataka
Expertise:
Cell Biology
55
Publications
0
Projects
3225
Scopus Citations
3277
CrossRef
19 Years 8 Months Total Experience
Scopus
3,225
Citations
28
h-index
CrossRef
3,277
Citations
28
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Professional Recognition
Postdoctoral fellowship
2004
American Heart Foundation, AHA
Senior Postdoctoral fellowship
2006
American Heart Foundation, AHA
The Wellcome Trust Foundation-UK, Senior Research Fellowship in Biomedical Sciences
2007
Wellcome Trust Foundation-UK
BM Birla Science Prize Award for Biological Sciences
2011
Birla Science Foundation
Young Researcher Award
2012
Sir Dorabji Tata and allied Trust
Swarnajayanthi Fellowship award in life sciences
2012
Ministry of Science and Technology, DST, Government of India
Nominated for GRC member
2012
GRC
National Bioscience award
2014
Department of Biotechnology, India
CDRI AWARDS -2016 for Excellence in Drug Research in Life Sciences
2016
CSIR-Central Drug Research Institute, Lucknow.
Sir. C.V. Raman Karnataka State Science award, Life Sciences
2017
Karnataka, State
Fellow of National Academy of Sciences
2017
National Academy of Sciences (NASI), Allahabad
Fellow of Indian Academy of Sciences
2024
Indian Academy of Sciences, Bangalore
Fellow of Indian National Science Academy
2025
INSA
Community & Membership
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Personal Details
Doctor of Philosophy
2000
Indian Institute of Technology, Hyderabad
Master of Science
1995
South Texas Veterans Health Care System, San Antonio, Texas, USA
Bachelor of Science
1993
N/A
Professor
Jan 2019 – Present
Indian Institute of Science, Bangalore
| Biochemistry
Associate Professor
Jan 2013 – Jan 2019
Indian Institute of Science, Bangalore
| Biochemistry
Assistant Professor
Jan 2007 – Jan 2013
Indian Statistical Institute Bangalore
Medical and Health Sciences
Scholarly Work
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Structure, function and dynamics of proteins by NMR spectroscopy: Application to human J-protein co -chaperone Dph4 and yeast Tim23-IMS
Unraveling the intricate architecture of human mitochondrial presequence translocase – Insights on its evolution and role in tumourigenesis
Role of Grp75 chaperone folding machinery in the maintenance of mitochondrial protein quality control
Understanding the dynamic organization of the presequence-translocase in the translocation of preproteins across mitochondrial inner membrane
Understanding in vivo significance of allosteric regularion in mtHsp70s: Revealing its implications in Parkinson’s disease progression
Uncovering the role of mitochondrial iron-sulfur (Fe-S) cluster biogenesis in human health and disease
Uncovering the role of mitochondrial co-chaperones and artificial antioxidants in cellular redox homeostasis
Understanding the role of ThiJ/DJ-1/PfpI family member proteins in regulating redox homeostasis, mitochondrial health and lifespan in Saccharomyces cerevisiae
Development of Nanomaterials as Antioxidant Enzyme Mimetics for Cellular Redox Homeostasis
Investigating the role of Tim17 and Mgr2 in regulating the architecture of presequence translocase and mitochondrial health
Understanding the structural organization of the carrier translocase machinery in regulating mitochondrial biogenesis and organelle quality control
Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression
Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revelaing its significance in Congenital Sideroblastic Anemia progression
Understanding the role of DNAJC30 and ISCU in mitochondrial homeostasis
Investigating DJ-1 homologs in maintaining genome integrity through glycation repair of macromolecules: Implications in regulating mitochondrial health
Deciphering the Role of DJ-1 Homologs in Alleviating Carbonyl and Oxidative Stress in Arabidopsis thaliana
Understanding the molecular mechanisms of redox-dependent mitochondrial homeostasis mediated by DJ-1 paralogs in Saccharomyces cerevisiae
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Scholarly Publications
Erratum: Organization of diphtheria toxin in membranes: A hydrophobic photolabeling study (Journal of Biological Chemistry (2000) 275: (11771-11777))
Open Access
Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study
Open AccessHydrophobic photolabeling as a new method for structural characterization of molten globule and related protein folding intermediates
Open AccessUnfolding of diphtheria toxin: Identification of hydrophobic sites exposed on lowering of pH by photolabeling
Open AccessAnalysis of protein folding using polarity-sensitive fluorescent probes
Scopus: 7
Regulated cycling of mitochondrial Hsp70 at the protein import channel
J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix
Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane
Showing 1 to 8 of 55 publications