Mugesh, G.
VIDWAN ID: 43174

Prof Mugesh, G.

Male Doctor of Philosophy
Dean | Inorganic and physical Chemistry
Indian Institute of Science, Bangalore
Karnataka
Expertise: Organic Chemistry
174 Publications
14 Projects
7192 Scopus Citations
10655 CrossRef
13 Years 9 Months Total Experience
Publications
174 Total
Articles
173
Chapters
1
Activity

No publication activity to display.

Scopus Scopus
7,192 Citations
42 h-index
CrossRef CrossRef
10,655 Citations
49 h-index
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Professional Recognition

Alexander von Humboldt Foundation Equipment Award
2005
Alexander von Humboldt Foundation
RSC West India Young Scientist Award
2010
Royal Society of Chemistry
IUPAC International Award
2005
International Union of Pure and Applied Chemistry
CDRI Award
2010
Central Drug Research Institute

Community & Membership

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Personal Details

Doctor of Philosophy
1998
N/A
Dean
Jan 2020 – Present
Indian Institute of Science, Bangalore | Inorganic and physical Chemistry
Professor
Dec 2012 – Apr 2020
Indian Institute of Science, Bangalore | Inorganic and physical Chemistry
Chemical Sciences
Organic Chemistry

Related Profiles

Scholarly Work

Regulation of Ferroptosis in Neuronal Cells
Other
Role: Other
Inhibition of deiodinase 3 for treating neuropsychiatric disorder
Completed
Role: Other
Prevention of eNOS Uncoupling by enzyme Mimetics: A Novel Therapeutic Approach for the Treatment of Endothlial Dysfunction in Vascular Disease
Other
Agency: Department of Science and Technology Role: Other
Peptide Aggregation in Neurodegenarative Diseases:Inhibition of Oxidative Amyloid-beta Aggregation by Antioxidant Nanozymes
Completed
Agency: Department of Science and Technology Role: Other
Peptide Aggregation in Neurodegenerative Diseases: Metal-mediated Tyrosine and Histidine Modifications in Amyloid beta-Peptides
Completed
Agency: Department of Science and Technology Role: Other
Development of selenazole drugs as a novel class of anti-cancer agents targeting the immune regulatoryenzyme indoleamine 2,3-dioxygenase
Completed
Role: Other
Glutathione Peroxidase and Peroxynitrite Reductase Mimetics
Completed
Role: Other
Bioinorganic Chemistry of Enzymatic Halogenations: Understanding the role of Redox Active Metalloproteins
Completed
Role: Other
Antibiotic Resistance and Zinc Hydrolases: Understanding the Role of Metallo-b-lactamases
Completed
Role: Other
Anti-Thyroid Drugs and Thyroid Hormone Synthesis
Completed
Role: Other
elenocysteine-mediated Native Chemical Ligation: Towards Total Chemical Synthesis of Metalloproteins
Completed
Role: Other
Application of Synthetic Organoselenium Compounds in Biochemical Deiodination Reactions
Completed
Role: Other
Chemically Modified Proteases: Mimics of Iodothyronine Deiodinases
Completed
Role: Other
Synthetic Selenium compounds as Mimics of Selenoenzyme
Other
Role: Other

Antioxidant Activity Of The Anti-Inflammatory Compound Ebselen And Its Analogues : Role Of Nonbonded Interactions

University Indian Institute of Science, Bengaluru
Year 2008
Downloads 0

Bio-inspired Materials : Antioxidant and Phosphotriesterase Nanozymes

University Indian Institute of Science, Bengaluru
Year 2014
Downloads 0

Biomimetic Studies On Anti-Thyroid Drugs And Thyroid Hormone Synthesis

University Indian Institute of Science, Bengaluru
Year 2007
Downloads 0

Biomimetic Studies on Tyrosine- and Phenolate- Based Ligands and their Metal Complexes

University Indian Institute of Science, Bengaluru
Year 2014
Downloads 0

Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics

University Indian Institute of Science, Bengaluru
Year 2013
Downloads 0

Design And Synthesis Of Novel Angiotensin Converting Enzyme (ACE) Inhibitors Having Antioxidant Activity

University Indian Institute of Science, Bengaluru
Year 2010
Downloads 0

The Effect of Substituents and Solvents on the Deiodination Reactions of Thyroid Hormones by Iodothyronine Deiodinase Mimics

University Indian Institute of Science, Bengaluru
Year 2016
Downloads 0

Halogen Bonding in the Structure and Biomimetic Dehalogenation of Thyroid Hormones and Halogenated Nucleosides

University Indian Institute of Science, Bengaluru
Year 2016
Downloads 0

Metallo-β-Lactamase, Phosphotriesterase And Their Functional Mimics

University Indian Institute of Science, Bengaluru
Year 2009
Downloads 0

Structure-Activity Correlation and Mechanistic Investigations of Glutathione Peroxidase-Like Catalytic Activity of Diaryl Diselenides

University Indian institute of Science, Bengaluru
Year 2014
Downloads 0

Synthetic Antioxidants : Structure-Activity Correlation Studies Of Glutathione Peroxidase Mimics And Peroxynitrite Scavengers

University Indian Institute of Science, Bengaluru
Year 2009
Downloads 0

Design and Synthesis of Cyclic Diselenides and Selenenyl Sulfides for Biomimetic Applications

University Indian Institute of Science Bengaluru
Year 2018
Downloads 0

Development of New Synthetic Methodologies for Selenocysteine, Selenopeptides and β-Seleno Amino Acids

University Indian Institute of Science Bengaluru
Year 2019
Downloads 0

TYPE III DEIODINASE INHIBITORS AND USES THEREOF

HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
Jerusalem
IL | INDIAN INSTITUTE OF SCIENCE
BANGALORE
IN | HADASIT MED RES SERVICE | INDIAN INST SCIENT
- Patent No. : US20190389799A1 Filed : 28-08-2019
Published : 17-08-2021 Granted

TYPE III DEIODINASE INHIBITORS AND USES THEREOF

HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
Jerusalem
IL | INDIAN INSTITUTE OF SCIENCE
Bangalore
IN | HADASIT MED RES SERVICE | INDIAN INST SCIENT
- Patent No. : US20180215709A1 Filed : 14-09-2016
Published : 02-08-2018 Published

3,4-BROMO ODER -SULFONAT-SUBSTITUIERTE 1H-PYRROLE-2,5-DION-DERIVATE ALS TYPE III DEIODINASE (DIO3) INHIBITOREN ZUR BEHANDLUNG VON DEPRESSIONEN UND KREBS | DÉRIVÉS 1H-PYRROLE-2,5-DIONE SUBSTITUÉS 3,4-BROMO OU -SULFONATE EN TANT QU'INHIBITEURS DE DÉIODINASE

HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
9112001 Jerusalem
IL
101672088 | Indian Institute Of Science
Bangalore 560012
IN
101405937
- Patent No. : EP3119768A1 Filed : 16-03-2015
Published : 25-01-2017 Published

INHIBITEURS DE LA DÉSIODINASE DE TYPE III ET LEURS UTILISATIONS | TYPE III DEIODINASE INHIBITORS AND USES THEREOF

HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
IL | INDIAN INSTITUTE OF SCIENCE
IN
- Patent No. : WO2015140792A1 Filed : 16-03-2015
Published : 24-09-2015 Published

Scholarly Publications

Intramolecular Se ⋯ N nonbonding interactions in low-valent organoselenium derivatives: A detailed study by 1H and 77Se NMR spectroscopy and X-ray crystallography

Journal Article
CHEMISTRY - A EUROPEAN JOURNAL. Year: 1999. Volume: 5 , Issue: 5 , Pages: 1411-1421 .

Aspects of organochalcogen (S, Se, Te) compounds stabilized by intramolecular coordination

Journal Article
Journal of Chemical Sciences. Year: 2000. Volume: 112 , Issue: 3 , Pages: 239-248 .
Authors: G. Mugesh; Arunashree Panda; Harkesh B. Singh

Structure-activity correlation between natural glutathione peroxidase (GPx) and mimics: A Biomimetic concept for the design and synthesis of more efficient GPx mimics

Journal Article

Structure-activity correlation between natural glutathione peroxidase (GPx) and mimics: A biomimetic concept for the design and synthesis of more efficient GPx mimics

Journal Article
Year: 2001.
Authors: DU MONT, WW; MUGESH, G

Tuning selenium-iodine contacts: From secondary soft-soft interactions to covalent bonds

Journal Article
Journal of Organometallic Chemistry. Year: 2001. Volume: 623 , Issue: 1-2 , Pages: 14-28 .
Authors: Wolf-Walther du Mont; Andreas Martens-von Salzen; Frank Ruthe; Emma Seppälä; Govindasamy Mugesh; Francesco A Devillanova; Vito Lippolis; Norbert Kuhn

Tuning selenium-iodine contacts: from secondary soft-soft interactions to covalent bonds (vol 623, pg 14, 2001)

Journal Article
Journal of Organometallic Chemistry. Year: 2001. Volume: 628 , Issue: 2 , Pages: 280 .
Authors: Devillanova, FA; Kuhn, N; Lippolis, V; Martens-von Salzen, A; Mugesh, G; Ruthe, F; Seppala, E; du Mont, WW

Intramolecularly coordinated organoselenium darivatives: Syntheses, structure and reactivity

Journal Article
Phosphorus Sulfur and Silicon and the Related Elements. Year: 2001. Volume: 171-172 , Pages: 187-205 .
Authors: Arunashree Panda; G. Mugesh; Harkesh B. Singh; Ray J. Butcher

Reactions of organoselenenyl iodides with thiouracil drugs: An enzyme mimetic study on the inhibition of iodothyronine deiodinase

Journal Article
Year: 2001.
Showing 25 to 32 of 174 publications