Siva Sundara Kumar Durairajan
VIDWAN ID: 65766

Prof Siva Sundara Kumar Durairajan

Male Doctor of Philosophy
Professor | Department Of Microbiology
Central University of Tamil Nadu, Tiruvarur
Tamil Nadu
Expertise: Biology
83 Publications
10 Projects
3207 Scopus Citations
2693 CrossRef
21 Years Total Experience
Publications
83 Total
Articles
62
Chapters
5
Proceedings
16
Activity

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Scopus Scopus
3,207 Citations
31 h-index
CrossRef CrossRef
2,693 Citations
30 h-index
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Professional Recognition

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Community & Membership

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Personal Details

Doctor of Philosophy
2004
Hindustan shipyard limited
Master of Technology
1999
Indian Institute of Technology, Ropar
Master of Science
1998
NMEICT (MHRD, GoI)
Bachelor of Science
1996
N/A
Professor
Sep 2024 – Present
Central University of Tamil Nadu, Tiruvarur | Department Of Microbiology
Associate Professor
Dec 2017 – Sep 2024
Central University of Tamil Nadu, Tiruvarur | Department Of Microbiology
Visiting Scientist
Apr 2017 – Apr 2017
Hong Kong Baptist University
Assistant Professor (Grade-II)
Apr 2012 – Mar 2017
Hong Kong Baptist University
Senior Research Associate
Jan 2012 – Apr 2012
Hong Kong Baptist University
Post-Doctoral Research Scientist
Aug 2006 – Jan 2012
Hong Kong Baptist University
Post-Doctoral Fellow
Feb 2005 – Aug 2006
National Health Research Institutes, Taiwan
Biological Sciences
Biology

Related Profiles

Scholarly Work

Aminocatalytic [4+2] Remote Annulation: Synthesis/DFT Studies and Anti-Alzheimer's Screening of Optically Pure Perhydroquinoline Scaffolds
Other
Role: Co-Principal Investigator Grant: CRG/2023/000535
Virtual and in vitro screening of spiropyrrolidine derivatives and DiversetTM core library small molecules to identify SARS-CoV-2 entry
Other
Role: Principal Investigator Grant: BT/PR4094/ COT/142/20/2021
Deciphering the role of Kinesin I heavy chain on the Tau phosphorylation and aggregation in Alzheimer
Other
Agency: Department of Science and Technology Role: Principal Investigator Grant: CRG/2018/001596
Investigation of Anti- Alzheimer's activity of Protopine derivative for clearing Tau through modulation of HDAC6- Hsp90 interplay and for improving memory via stimulation of RAS-GRF1/ERK pathway
Completed
Role: Co-Principal Investigator
Potential repositioning of antiepileptic drugs for the treatment of Alzheimer
Completed
Role: Principal Investigator
Alzheimer's Disease: From Detection
Completed
Role: Co-Principal Investigator Grant: C2012-15G
Development of NeuroDefend: A traditional Chinese medicine formula optimized for treating Alzheimer’s disease and other tauopathies
Completed
Role: Principal Investigator Grant: ITS/253/14
Neuropharmacological and Chemical-genetical Approaches to Investigate the Therapeutic Effects of Yuanhu Zhitong Prescription in Treating Alzheimer
Completed
Role: Principal Investigator
Structural modification of protopine alkaloid from the Chinese herbal medicine Yanhusuo for the optimization of anti-Alzheimer's disease activity
Completed
Role: Principal Investigator Grant: ITS//187/13
An In Vivo Investigation of The Therapeutic Effects of Modified Huang-Lian-Jie-Du-Tang and Its Combination with a Western Drug memantin
Completed
Role: Principal Investigator
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Licochalcone-A and/or Its Derivatives For Inducing Neuronal Differentiation

Central University of Tamil Nadu
- Application No. : 01941038499 A Filed : 24-09-2019
Published : 26-03-2021 Filed

草药组合物及其治疗神经退行性疾病的用途

Hong Kong Baptist University
- Patent No. : 20190282646 Filed : 15-03-2019
Published : 24-09-2019 Filed

Uses and Development of Neurodefend for Treating Neurodegenerative Diseases

Hong Kong Baptist University
- Patent No. : US 20190282646A1 Filed : 14-12-2018
Published : 19-09-2019 Published

Composition comprising Rhizoma Coptidis, Cortex Phellodendri and Fructus Gardeniae and For Treating Neurodegenerative Diseases

Hong Kong Baptist University
- Patent No. : US009375457B2 Filed : 13-06-2014
Published : 28-07-2016 Published

包含黄连、黄柏以及栀子并且用于治疗神经变性疾病的组合物

Hong Kong Baptist University
- Patent No. : 104225023 Filed : 13-06-2014
Published : 25-07-2017 Published

Scholarly Publications

Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease

Open Access
Journal Article
Frontiers in Pharmacology. Year: 2020. Volume: 11 .
Authors: A. Iyaswamy; S. K. Krishnamoorthi; Y. W. Liu; J. X. Song; A. K. Kammala; S. G. Sreenivasmurthy; S. Malampati; B. C. K. Tong; K. Selvarasu; K. H. Cheung; J. H. Lu; J. Q. Tan; C. Y. Huang; S. S. K. Durairajan; M. Li

Isolation and Detection of Pathological Tau Species in a Tauopathy Mouse Model

Book Chapter
Year: 2024. Volume: 2761 , Pages: 317-328 .
Authors: Abhay Kumar Singh; Karthikeyan Selvarasu; Siva Sundara Kumar Durairajan

Unraveling the interplay of kinesin-1, tau, and microtubules in neurodegeneration associated with Alzheimer’s disease

Open Access
Review
Frontiers in Cellular Neuroscience. Year: 2024. Volume: 18 .
Authors: Siva Sundara Kumar Durairajan; Karthikeyan Selvarasu; Abhay Kumar Singh; Supriti Patnaik; Ashok Iyaswamy; Yogini Jaiswal; Leonard L. Williams; Jian-Dong Huang

Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models

Open Access
Journal Article
Frontiers in Molecular Biosciences. Year: 2022. Volume: 9 .
Authors: Karthikeyan Selvarasu; Abhay Kumar Singh; Ashok Iyaswamy; Sravan Gopalkrishnashetty Sreenivasmurthy; Senthilkumar Krishnamoorthi; Amal Kanti Bera; Jian-Dong Huang; Siva Sundara Kumar Durairajan

Pharmaceutical Potential of Marine Fungal Endophytes

Book Chapter
Year: 2019. Pages: 283-305 .
Authors: Rajesh Jeewon; Amiirah Bibi Luckhun; Vishwakalyan Bhoyroo; Nabeelah B. Sadeer; Mohamad Fawzi Mahomoodally; Sillma Rampadarath; Daneshwar Puchooa; V. Venkateswara Sarma; Siva Sundara Kumar Durairajan; Kevin D. Hyde

Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease

Journal Article
Phytomedicine. Year: 2021. Volume: 91 .
Authors: Ashok Iyaswamy; Senthil Kumar Krishnamoorthi; Huan Zhang; Sravan G. Sreenivasmurthy; Zhou Zhu; Jia Liu; Cheng-Fu Su; Xin-Jie Guan; Zi-Ying Wang; King-Ho Cheung; Ju-Xian Song; Siva Sundara Kumar Durairajan; Min Li

A Novel Species of Penicillium With Inhibitory Effects Against Pyricularia oryzae and Fungal Pathogens Inducing Citrus Diseases

Open Access
Journal Article
Authors: Li-Juan Liang; Rajesh Jeewon; Pem Dhandevi; Siva Sundara Kumar Durairajan; Hongye Li; Fu-Cheng Lin; Hong-Kai Wang

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

Open Access
Journal Article
Autophagy. Year: 2021. Volume: 17 , Issue: 5 , Pages: 1112-1130 .
Authors: Cui-Zan Cai; Chuanbin Yang; Xu-Xu Zhuang; Ning-Ning Yuan; Ming-Yue Wu; Jie-Qiong Tan; Ju-Xian Song; King-Ho Cheung; Huanxing Su; Yi-Tao Wang; Bei-Sha Tang; Christian Behrends; Siva Sundara Kumar Durairajan; Zhenyu Yue; Min Li; Jia-Hong Lu