Ministry of Education
Harikumar K B
VIDWAN ID: 63696

Dr Harikumar K B

Male Doctor of Philosophy
Scientist E1
Rajiv Gandhi Centre for Biotechnology
Kerala
Expertise: Biochemistry and Molecular Biology
ORCID 0000-0002-1763-4179 Scopus 23667640200 Google Scholar 0-6vGiYAAAAJ
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104 Publications
0 Projects
13395 Scopus Citations
12205 CrossRef
14 Years 6 Months Total Experience
Publications
104 Total
Articles
93
Books
5
Chapters
6
Activity

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Scopus Scopus
13,395 Citations
36 h-index
CrossRef CrossRef
12,205 Citations
39 h-index
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Professional Recognition

Ramalingaswami Fellowship
2012
Department of Biotechnology, Government of India
Fast track fellowship
2013
Department of Science and Technology, Government of India
Travel award
2014
Centre for International Co-operation in Science (CICS), Chennai

Community & Membership

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Indian Association for Cancer Research
Life Member
Jan 2012

Personal Details

Doctor of Philosophy
2008
N/A
Master of Science
2001
N/A
Bachelor of Science
1999
N/A
Scientist E1
Mar 2018 – Present
Rajiv Gandhi Centre for Biotechnology
Scientist C
Mar 2012 – Mar 2018
Rajiv Gandhi Centre for Biotechnology
Medical and Health Sciences
Biochemistry and Molecular Biology

Related Profiles

Scholarly Work

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Scholarly Publications

Uttroside B, a US FDA-designated ‘Orphan Drug’, mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3

Open Access
Journal Article
Cell Death Discovery. Year: 2026. Volume: 12 , Issue: 1 .
Authors: Chenicheri Kizhakkeveettil Keerthana; Tennyson P. Rayginia; Kalishwaralal Kalimuthu; Sandhini Saha; Nair H. Haritha; Amrutha Nisthul Areekkara; Mundanattu Swetha; Sreekumar U. Aiswarya; Lekshmi R. Nath; Sanjay Suresh Varma; Arun Viswanathan; Jannet S; Shirly J; Aparna JS; Archana Praveen; Vishnu Sunil Jaikumar; Sankar Sundaram; Nikhil Ponnoor Anto; Tushar K. Maiti; C Sadasivan; Noah Isakov; Ravi S. Lankalapalli; Kuzhuvelil B. Harikumar; Ruby John Anto
DOI 10.1038/s41420-026-03055-5

Computational drug repurposing of Akt-1 allosteric inhibitors for non-small cell lung cancer

Open Access
Journal Article
Scientific Reports. Year: 2023. Volume: 13 , Issue: 1 .
Authors: Krishnaprasad Baby; Swastika Maity; Chetan Hasmukh Mehta; Usha Y. Nayak; Gautham G. Shenoy; Karkala Sreedhara Ranganath Pai; Kuzhuvelil B. Harikumar; Yogendra Nayak
DOI 10.1038/s41598-023-35122-7 Crossref Crossref: 38 Scopus Scopus: 34

A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated ‘Orphan Drug’, for the Treatment of Hepatocellular Carcinoma

Journal Article
Anti-Cancer Agents in Medicinal Chemistry. Year: 2024. Volume: 24 , Issue: 19 , Pages: 1431-1441 .
Authors: Chenicheri Kizhakkeveettil Keerthana; Sreekumar U. Aiswarya; Tennyson P. Rayginia; Yadu Vijayan; Shirly James; Sadiq C. Shifana; Sankar Sundaram; D.K. Induja; Ravi S. Lankalapalli; Kuzhuvelil B. Harikumar; Ruby John Anto
DOI 10.2174/0118715206316190240527160242 Crossref Crossref: 4 Scopus Scopus: 3

Modification of Cysteine Residue in p65 Subunit of Nuclear Factor-κB (NF-κB) by Picroliv Suppresses NF-κB-Regulated Gene Products and Potentiates Apoptosis (Retraction of Vol 68, Pg 8861, 2008)

Journal Article
Cancer Research. Year: 2018. Volume: 78 , Issue: 17 , Pages: 5187-5187 .
Authors: Anand, P.; Kunnumakkara, A. B.; Harikumar, K. B.; Ahn, K. S.; Aggarwal, B. B.
DOI 10.1158/0008-5472.CAN-18-1824

Immunomodulatory properties of D-sorbitol/D-mannitol incorporated linear step-growth <i>Co</i>-polymers

Journal Article
International Journal of Polymeric Materials and Polymeric Biomaterials. Year: 2023. Volume: 72 , Issue: 9 , Pages: 690-701 .
Authors: S. Kiran; J. Parvathy; Thenmozhi Sukumaran; Jeslin Varghese; S Lakshmi; Sreesha S. Kumar; Anu Babu; Kuzhuvelil B. Harikumar; Lakshminarayanan Ragupathy
DOI 10.1080/00914037.2022.2052726 Crossref Crossref: 3 Scopus Scopus: 3

Therapeutic options in hepatocellular carcinoma: a comprehensive review

Open Access
Journal Article
Clinical and Experimental Medicine. Year: 2023. Volume: 23 , Issue: 6 , Pages: 1901-1916 .
Authors: Suresh, Diwakar; Srinivas, Akshatha N.; Prashant, Akila; Harikumar, Kuzhuvelil B.; Kumar, Divya P.
DOI 10.1007/S10238-023-01014-3 Crossref Crossref: 47 Scopus Scopus: 50

Orphan drug uttroside B impedes MASH progression and HCC development in experimental models

Open Access
Journal Article
JHEP Reports. Year: 2026. Volume: 8 , Issue: 2 .
Authors: Tennyson P. Rayginia; Chenicheri K. Keerthana; Sreekumar U. Aiswarya; Sadiq C. Shifana; S. Jannet; Sanjay Suresh Varma; P. Maria Joy; Mundanattu Swetha; Shirly James; J.S. Aparna; Yadu Vijayan; Archana Payickattu Retnakumary; Lekshmi R. Nath; Kalishwaralal Kalimuthu; Vishnu Sunil Jaikumar; Sankar Sundaram; Nikhil Ponnoor Anto; Noah Isakov; Kuzhuvelil B. Harikumar; Ravi S. Lankalapalli; Ruby John Anto
DOI 10.1016/j.jhepr.2025.101626

Navigating the complexities of epigenetic dysregulation in breast cancer and its implication in therapeutic interventions: a comprehensive overview

Journal Article
Molecular and Cellular Biochemistry. Year: 2026. Volume: 481 , Issue: 1 , Pages: 171-186 .
Authors: Swathy Ravindran; Ravindran Vini; Arumugam Rajavelu; Kuzhuvelil B. Harikumar; Sreeharshan Sreeja
DOI 10.1007/s11010-025-05415-8 Crossref Crossref: 4 Scopus Scopus: 4
Showing 1 to 8 of 104 publications