Saravanan Matheshwaran
VIDWAN ID: 52308

Prof Saravanan Matheshwaran

Male Doctor of Philosophy
Associate Professor | Department of Biological Sciences and Bioengineering
Indian Institute of Technology, Kanpur
Uttar Pradesh
Expertise: Biotechnology and Applied Microbiology
27 Publications
16 Projects
221 Scopus Citations
227 CrossRef
13 Years 4 Months Total Experience
Publications
27 Total
Articles
26
Chapters
1
Activity

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Scopus Scopus
221 Citations
7 h-index
CrossRef CrossRef
227 Citations
8 h-index
Google Scholar Google Scholar

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Professional Recognition

INSA Medal for Young Scientists
2010
Indian National Science Academy, New Delhi
EMBO Fellowship
2009
European Molecular Biology Organization- Long Term Fellowship
EIPOD-Marie Curie fellowship
2012
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
Sreenivasya Medal for Best PhD Thesis
2008
Indian Institute of Science Bangalore
Innovative Young Biotechnologist Award
2016
DBT

Community & Membership

UK Research and Innovation (UKRI) International Development Peer Review College
Member
Jan 2018 – Jan 2021
Society of Biological Chemists (SBCI) India
Executive committee member
Jan 2018
Asian Federation of Biotechnology - AFOB
Steering Committee Member
Jun 2024
ANTIMICROBIAL RESISTANCE RESEARCH SOCIETY OF INDIA
Vice President
Apr 2026
Biogroup India
Founder
Jan 2018
Indian Biofilms Society
LIFE MEMBER
Jan 2025
Society of Biological Chemists India
LIFE MEMBER
Jan 2005
Antimicrobial Resistance Research Society of India
LIFE MEMBER
Jan 2026

Personal Details

Doctor of Philosophy
2008
Indian Institute of Technology, Delhi
Associate Professor
May 2013 – Present
Indian Institute of Technology, Kanpur | Department of Biological Sciences and Bioengineering
Medical and Health Sciences
Biotechnology and Applied Microbiology

Related Profiles

Scholarly Work

Deciphering the role of Ustilago maydis SWR1 chromatin remodeler in melanin biosynthesis, morphogenesis, and virulence mechanism
Other
Agency: Department of Bio-Technology Role: Principal Investigator
Small Molecule Inhibitors to cripple mycobacterial "SOS" response mutagenic axis to combat AMR
Other
Agency: Indian Council of Medical Research Role: Principal Investigator
Deciphering the role of LexA-family transcription regulator induced mutageneisis and AMR of MDR strain of Acinetobacter baumannii
Other
Role: Principal Investigator
Treatment Of Organics-Laden Industrial Wastewater Effluent Under Flow Conditions Using Photobioreactor-Integrated Microbial Fuel Cell
Completed
Agency: Department of Bio-Technology Role: Co-Principal Investigator
Deciphering of role of nuclear actin related protein (Arp8) in rRNA recognition- Role beyond chromatin remodelling
Other
Role: Principal Investigator
Understanding The Mechanism Of Mg2+ Mediated Sos Induction In Mycobacterium Tuberculosis To Declipher Its Role In Antibiotic Resistance And Survival In Macrophage
Other
Agency: Department of Secondary and Higher Education Role: Principal Investigator
Genome wide identification and functional characterization of the effector genes of Phytophthora drechsleri Tucker F. sp. cajani causing Phytohthora blight in Pigeonpea
Other
Role: Co-Principal Investigator
Nanoscale Zeolite-Zinc-Carbo-Mycolyzers (Zinocarbolyzers) to improve productivity of rice. Project Duration
Other
Agency: Department of Bio-Technology Role: Co-Principal Investigator
Development of 3D printable bone and nerve guiding drug eluting composite implants for vertebral/spine trauma in infection/tuberculosis and cancer Project Duration
Other
Agency: Department of Secondary and Higher Education Role: Co-Principal Investigator
Understanding the role of a putative antibiotic methyltransferase Rv1377c from Mycobacterium tuberculosis in antibiotic resistance and persisters formation
Other
Agency: Indian Council of Medical Research Role: Principal Investigator
Understanding The Role Of SOS-Regulated HNH Nucleases Of Mycobacterium Tuberculosis In Latency And Reactivation Amount
Completed
Role: Principal Investigator
Deciphering The Roles Of Mycobacterial "SOS" Response Regulated Toxin-Antitoxin (VapBC40) Module In Persistence And Antibiotic Resistance
Completed
Agency: Department of Bio-Technology Role: Principal Investigator
Role Of SWR1 Chromatin Remodeling Complex In Radiation Resistance Fungus "Ustilago Maydis
Completed
Role: Principal Investigator
A smart phone based dark field microscope for point of care diagnostic of blood cell disorder in lethal diseases Project Duration
Completed
Agency: Department of Secondary and Higher Education Role: Co-Principal Investigator
Proteins from Mycobacterium Tuberculosis and Proteins Involved in Chromatin Transactions Under The Centre Of Excellence In Chemical Biology
Completed
Agency: Department of Secondary and Higher Education Role: Co-Principal Investigator
Molecular & Biochemical Characterixation Of Sachharomyces Cerevisiae Actin Related Protein 8 (Arp8
Completed
Role: Principal Investigator

Effect of chemical cues on the regulation of Bacillus subtilis lifestyle

University Indian Institute of Technology Kanpur
Year 2024
Downloads 0

Targeting master regulator LexA to toggle SOS response: tactics to regulate the mutagenic balance in mycobacteria

University Indian Institute of Technology Kanpur
Year 2024
Downloads 0

Investigation of biogeochemical processes governing arsenic release in mixed-oxic state groundwater in the middle-gangetic plains of India

University Indian Institute of Technology Kanpur
Year 2024
Downloads 0

SWR1-CHROMATIN REMODELER AS A CENTRAL REGULATOR OF METABOLIC BALANCE AND BIOTROPHIC DEVELOPMENT IN USTILAGO MAYDIS

University IIT Kanpur
Year 2026
Downloads 0

Copper(II) based antimicrobial agents for attenuation of in-vivo dental biofilm formation

Gautam R
Chaudhary K
Agrahari B
Saravanan M
Misra SK
Biswas B
Chatterjee N
Kumar A
Chaudhary A
Sonker H
Dewan S
- Application No. : 202411029788 Filed : 12-04-2024
Published : 30-11--0001 Granted

ANTIBACTERIAL PLATINUM-N-HETEROCYCLIC CARBENECOMPOUNDS AND PROCESS OF PREPARATION THEREOF

INDIAN INSTITUTE OF TECHNOLOGY KANPUR | CSIR CENTRAL DRUG RESEARCH INSTITUTE
- Patent No. : IN201911025087A Filed : 24-06-2019
Published : 05-07-2019 Published

Variant of KpnI restriction endonuclease

2.Nagaraja V
Saravanan Matheshwaran and Zhu Z
- Application No. : US 08119382 B2 Filed : 12-02-2012
Published : 30-11--0001 Granted

KpnI Restriction endonuclease with reduced star activity

1.Zhu Z
Nagaraja V and Saravanan Matheshwaran
- Application No. : EP 1 931773 B1 Filed : 29-12-2010
Published : 30-11--0001 Granted

Scholarly Publications

A new type II restriction endonuclease, OfoI from nonheterocystous cyanobacterium Oscillatoria foreaui

Journal Article
Current Science. Year: 2003. Volume: 85 , Issue: 2 , Pages: 188-191 .

Ca2+-mediated site-specific DNA cleavage and suppression of promiscuous activity of KpnI restriction endonuclease

Open Access
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2004. Volume: 279 , Issue: 48 , Pages: 49736-49740 .
Authors: Siddamadappa Chandrashekaran; Matheshwaran Saravanan; Deshpande R. Radha; Valakunja Nagaraja

Type II restriction endonuclease R.Kpnl is a member of the HNH nuclease superfamily

Open Access
Journal Article
Nucleic Acids Research. Year: 2004. Volume: 32 , Issue: 20 , Pages: 6129-6135 .
Authors: Matheshwaran Saravanan; Janusz M. Bujnicki; Iwona A. Cymerman; Desirazu N. Rao; Valakunja Nagaraja

R.Kpnl, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+

Open Access
Journal Article
Nucleic Acids Research. Year: 2007. Volume: 35 , Issue: 8 , Pages: 2777-2786 .
Authors: M. Saravanan; K. Vasu; R. Kanakaraj; D. N. Rao; V. Nagaraja

Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease

Open Access
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2007. Volume: 282 , Issue: 44 , Pages: 32320-32326 .
Authors: Matheshwaran Saravanan; Kommireddy Vasu; Soumitra Ghosh; Valakunja Nagaraja

Structural integrity of the Beta Beta Alpha-Metal finger motif is required for DNA binding and stable protein-DNA complex formation in R.KpnI

Journal Article
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. Year: 2008. Volume: 1784 , Issue: 2 , Pages: 269-275 .
Authors: Kommireddy Vasu; Matheshwaran Saravanan; Janusz M. Bujnicki; Valakunja Nagaraja

Evolution of sequence specificity in a restriction endonuclease by a point mutation

Journal Article
Proceedings of the National Academy of Sciences (PNAS). Year: 2008. Volume: 105 , Issue: 30 , Pages: 10344-10347 .
Authors: Matheshwaran Saravanan; Kommireddy Vasu; Valakunja Nagaraja

Conformational Changes Triggered by Mg 2+ Mediate Transactivator Function

Journal Article
Biochemistry. Year: 2009. Volume: 48 , Issue: 11 , Pages: 2347-2354 .
Authors: Ganduri Swapna; Matheswaran Saravanan; Valakunja Nagaraja
Showing 1 to 8 of 27 publications