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Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme
Authors: Ibidapo S. Williams; Shifali Chib; Vijay K. Nuthakki; Linda Gatchie; Prashant Joshi; Niteen A. Narkhede; Ram A. Vishwakarma; Sandip B. Bharate; Saurabh Saran; Bhabatosh Chaudhuri
Synthesis and Biological Evaluation of Colchicine─Aryl/Alkyl Amine Hybrids as Potential Noncytotoxic Cholinesterase Inhibitors: Identification of SBN-284 as a Dual Inhibitor of Cholinesterases and NLRP3 Inflammasome
Authors: Chilakala Nagarjuna Reddy; Vijay K. Nuthakki; Ankita Sharma; Sumera Malik; Misbah Tabassum; Rajesh Kumar; Sushil Choudhary; Fiza Iqbal; Ziya Tufail; Dilip M. Mondhe; Ajay Kumar; Sandip B. Bharate
Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer’s Disease: Discovery of SB-1448