Tapas Manna
VIDWAN ID: 49303

Prof Tapas Manna

Male Doctor of Philosophy
Professor | School of Biology
Indian Institute of Science Education & Research (IISER), Thiruvananthapuram
Kerala
Expertise: Cell Biology
36 Publications
9 Projects
1339 Scopus Citations
1292 CrossRef
16 Years 7 Months Total Experience
Publications
36 Total
Articles
36
Activity

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Scopus Scopus
1,339 Citations
18 h-index
CrossRef CrossRef
1,292 Citations
18 h-index
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Professional Recognition

S Ramachandran National Bioscience Award for Career Development
2019
Department of Biotechnology,Ministry of Science & Technology, Government of India
Fellow of the Indian National Science Academy
2025
Indian National Science Academy, New Delhi
Fellow of National Academy of Sciences, India
2025
National Science Academy of Sciences, India

Community & Membership

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American Society for Cell Biology
Regular Member
Jan 2019
Indian Society for Cell Biology
Life Member
Jan 2016
Indian Science Congress
Regular Member
Jan 2017
Society for Biological Chemists
Life Member
Jan 2017

Personal Details

Doctor of Philosophy
2004
N/A
Master of Science
1997
N/A
Bachelor of Science
1995
N/A
Professor
Jan 2020 – Present
Indian Institute of Science Education & Research (IISER), Thiruvananthapuram | School of Biology
Associate Professor
Sep 2014 – Apr 2019
Indian Institute of Science Education & Research (IISER), Thiruvananthapuram | School of Biology
Assistant Professor
Jun 2009 – Sep 2014
Indian Institute of Science Education & Research (IISER), Thiruvananthapuram | School of Biology
Medical and Health Sciences
Cell Biology

Related Profiles

Scholarly Work

Understanding the regulation of kinetochore protein phosphorylation for the activation of spindle assembly check-point
Other
Role: Other Grant: CRG/2020/002452
The role of colonic hepatic Tumor Over-expressed Gene (chTOG) in regulation of kinetochore size and fidelity of mitotic chromosome segregation
Other
Agency: Department of Bio-Technology Role: Other Grant: BT/HRD-NBA-NWB/38/2019-20(7
Identification and characterization of the molecular factors for the quality-control of kinetochore size and fidelity of spindle-chromosome attachment
Other
Agency: Department of Bio-Technology Role: Principal Investigator Grant: BT/PR30271/BRB/10/1740/2018
Elucidating the role of GTP-induced transition of EB1 dimer to monomer in the regulation of microtubule plus ends
Other
Agency: Council of Scientific and Industrial Research Role: Principal Investigator Grant: 37(1688)/17-EMR-II
To determine the role of ubiquitin ligase SCF-FBXW7 in regulation of centriole biogenesis and duplication in human cells
Other
Agency: Department of Science and Technology Role: Principal Investigator Grant: EMR/2016/001562
Determining the role of microtubule plus tip protein EB1 in regulation of spindle- kinetochore associated protein complex Ska: the mechanism underlying the stabilization of spindle- kinetochore attachment
Other
Agency: Department of Bio-Technology Role: Principal Investigator Grant: BT/PR12514/BRB/10/1352/2014
Determining the role of centrosome protein TACC3 in regulation of microtubule nucleation and elucidating its molecular mechanism
Completed
Agency: Department of Atomic Energy Role: Principal Investigator Grant: 2013/37B/68/BRNS/37063
To determine the molecular mechanisms involved in centrosomal transforming acidic coiled coil 3 (TACC3) mediated cell cycle progression
Completed
Agency: Department of Science and Technology Role: Principal Investigator Grant: SR/SO/BB-045/2010
To determine the structure-function aspects of microtubule end binding proteins
Completed
Agency: Council of Scientific and Industrial Research Role: Principal Investigator Grant: 37/(1433)/10/EMR-II

Regulation of Centrosome- Mediated Microtubule Nucleation: Role of Human Transforming Acidic Coiled- Coil 3 (TACC3

University IISER Thiruvananthapuram
Year 2016
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Structure-Function aspects of Microtubule Regulation by its Plus End Binding Protien and Interacting Novel Small Molecule Inhibitor

University IISER Thiruvananthapuram
Year 2016
Downloads 0

Role of Microtubule Plus End Binding Protein EB1 in Regulation of Spindle-Kinetochore Interaction During Mitosis

University IISER Thiruvananthapuram
Year 2016
Downloads 0

Determination of the structural and molecular basis of human centriole assembly

University IISER Thiruvananthapuram
Year 2019
Downloads 0

Regulation of Centriole Biogenesis by E3 Ubiquitin Ligase FBXW7

University IISER, Thiruvananthapuram
Year 2021
Downloads 0

Role of transforming acidic coiled-coil 3 (TACC3) in the regulation of microtubule assembly at the centrosomes

University IISER Thiruvananthapuram
Year 2022
Downloads 0

Elucidating the role of interaction of Ska1 with EB1 in regulation of kinetochore-microtubule attachment in human cells

University IISER Thiruvananthapuram
Year 2023
Downloads 0

Regulation of microtubule - chromosome attachment by Cytoskeleton Associated Protein 5 (CKAP5

University IISER Thiruvananthapuram
Year 2024
Downloads 0

Elucidating the role of E3 ubiquitin ligase, FBXW7 in regulation of mitotic progression in human cells

University IISER Thiruvananthapuram
Year 2024
Downloads 0

Molecular mechanisms underlying E3 ubiquitin ligase FBXW7-mediated control of centriole duplication

University IISER Thiruvananthapuram
Year 2026
Downloads 0
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Scholarly Publications

Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex

Open Access
Journal Article
BMC Molecular and Cell Biology. Year: 2019. Volume: 20 , Issue: 1 .
Authors: Resmi Rajeev; Puja Singh; Ananya Asmita; Ushma Anand; Tapas K. Manna

The ubiquitin ligase FBXW7 targets the centriolar assembly protein HsSAS-6 for degradation and thereby regulates centriole duplication

Open Access
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2020. Volume: 295 , Issue: 14 , Pages: 4428-4437 .
Authors: Binshad Badarudeen; Ria Gupta; Sreeja V. Nair; Aneesh Chandrasekharan; Tapas K. Manna

SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells

Open Access
Journal Article
Current Biology. Year: 2020. Volume: 30 , Issue: 12 , Pages: 2395-2403.e4 .
Authors: Hindol Gupta; Resmi Rajeev; Ranjan Sasmal; Renjith M. Radhakrishnan; Ushma Anand; Haritha Chandran; Nurni R. Aparna; Sarit Agasti; Tapas K. Manna

SxIP binding disrupts the constitutive homodimer interface of EB1 and stabilizes EB1 monomer

Open Access
Journal Article
Biophysical Journal. Year: 2021. Volume: 120 , Issue: 10 , Pages: 2019-2029 .
Authors: Shine Ayyappan; Pooja S. Dharan; Arya Krishnan; Renjith R. Marira; Mahil Lambert; Tapas K. Manna; Vinesh Vijayan

Ubiquitin signaling in the control of centriole duplication

Review
THE FEBS JOURNAL (ELECTRONIC). Year: 2022. Volume: 289 , Issue: 16 , Pages: 4830-4849 .
Authors: Binshad Badarudeen; Ushma Anand; Swarnendu Mukhopadhyay; Tapas K. Manna

Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1

Open Access
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2023. Volume: 299 , Issue: 2 .
Authors: Renjith M. Radhakrishnan; Safwa T. Kizhakkeduth; Vishnu M. Nair; Shine Ayyappan; R. Bhagya Lakshmi; Neethu Babu; Anjaly Prasannajith; Kenichi Umeda; Vinesh Vijayan; Noriyuki Kodera; Tapas K. Manna

TACC3-ch-TOG interaction regulates spindle microtubule assembly by controlling centrosomal recruitment of γ-TuRC

Open Access
Journal Article
Bioscience Reports. Year: 2023. Volume: 43 , Issue: 3 .
Authors: Resmi Rajeev; Swarnendu Mukhopadhyay; Suresh Bhagyanath; Manu Rani S. Devu Priya; Tapas K. Manna

E3-ubiquitin ligase, FBXW7 regulates mitotic progression by targeting BubR1 for ubiquitin-mediated degradation

Journal Article
Cellular and Molecular Life Sciences. Year: 2023. Volume: 80 , Issue: 12 .
Authors: Vishnu M. Nair; Amit Santhu Sabu; Ahmed Hussain; Delvin P. Kombarakkaran; R. Bhagya Lakshmi; Tapas K. Manna
Showing 1 to 8 of 36 publications