Rajalakshmi Manikkam
VIDWAN ID: 455680

Dr Rajalakshmi Manikkam

Female Doctor of Philosophy
Head | Department of Biotechnology and Bioinformatics
Holy Cross College, Tiruchirappalli
Tamil Nadu
Expertise: Medicinal Chemistry
40 Publications
0 Projects
641 Scopus Citations
395 CrossRef
27 Years 1 Month Total Experience
Publications
40 Total
Articles
33
Chapters
7
Activity

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Scopus Scopus
641 Citations
13 h-index
CrossRef CrossRef
395 Citations
12 h-index
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Professional Recognition

Dr P Daisy Memorial Gold Medal Oration Award
2018
Society for Reproductive Biology & comparative Endocrinology
Member in Reproduction & Endocrinology Award
2015
Society for Reproductive Biology & comparative Endocrinology
Prof. N.J. Chinoy Award
2009
Society for Reproductive Biology & comparative Endocrinology
Fellowship in Reproductive Biology & Comparative Endocrinology
2024
Society for Reproductive Biology & Comparative Endocrinology

Community & Membership

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Society for Reproductive Biology and Comparative Endocrinology
Life and Executive Member
Jan 2009
Bioinformatics and Drug Discovery Society
Life member
Jan 2017
Indian Association of Biomedical Scientists
Life member
Jan 2022
Society for Biotechnologists – India
Life Member
Jan 2021

Personal Details

Doctor of Philosophy
2010
NATIONAL COUNCIL FOR CEMENT AND BUILDING MATERIALS
Master of Philosophy
2003
Remote Sensing Applications Division
Master of Science
1997
N/A
Bachelor of Science
1995
N/A
Head
Aug 2007 – Present
Holy Cross College, Tiruchirappalli | Department of Biotechnology and Bioinformatics
Assistant Professor
Jun 1999 – May 2007
Shrimati Indira Gandhi College, Tiruchirappalli - 620 002. | Department of Biochemistry
Medical and Health Sciences
Medicinal Chemistry

Related Profiles

Scholarly Work

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Pharmacological and computational evaluation of novel triterpenoids isolated from ethyl acetate extract of Cassia fistula stem bark for anti-diabetic activity in STZ-induced type 1 diabetic albino male Wistar rats

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2022
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Impact of polysaccharide isolated from methanol extract of Tinospora cordifolia stem on breast cancer- in-vitro, in-vivo and in-silico approaches

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2020
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Knowledge based computational approach for target identification and prediction of side- effects of anti-cancer drugs

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2018
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Anticancer potentials of costunolide isolated from Costus speciosus on breast cancer

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2017
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Impact of dihydroxy gymnemic triacetate isolated from Gymnema sylvestre on prostate cancer - in-silico, in-vitro and in-vivo analysis

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2017
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A study on anticancer and chemopreventive effect of octyl gallate and gallic acid isolated from Terminalia bellarica against breast cancer

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2016
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In silico and in vitro approaches to design new inhibitors targeting DNA of Staphylococcus aureus

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2015
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Anti diabetic and anti cancer effects of gold nanoparticles synthesized from active principles of Cassia fistula(stem bark

University Holy Cross College(Autonomous), Bharathidasan University, Tiruchirappalli
Year 2015
Downloads 0

Molecular mechanisms underlying the hypoglycemic and antilipidemic potential of compound extracted from Scoparia dulcis in high-fat diet and streptozotocin-induced type 2 diabetes rats

University Bharathidasan University, Tiruchirappalli, Tamil Nadu
Year 2026
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Exploring the molecular pathways underlying the anti-cancer potential of the novel triterpenoid in regulating cell growth and proliferation in MCF-7 and MDA-MB-231 Breast cancer cell lines

University Bharathidasan University, Tiruchirappalli, Tamil Nadu
Year 2026
Downloads 0

A process for preparation of a novel compound-1 from methanol extract of Tinospora cordifolia stem with anti-diabetic property

Dr M Rajalakshmi
- Application No. : 4832/CHE/2012 Filed : 20-11-2012
Published : 20-11-2011 Published

A process for the preparation of a novel compounds-2 from ethyl acetate extract of Cassia fistula stem bark with anti-diabetic property

Dr M Rajalakshmi
- Patent No. : 305967 Filed : 17-07-2012
Published : 17-07-2012 Granted

A process for the preparation of a novel compounds-3 from ethyl acetate extract of Cassia fistula stem bark with anti-diabetic property

Dr M Rajalakshmi
- Patent No. : 397710 Filed : 17-07-2012
Published : 17-07-2012 Granted

A process for the preparation of a novel compounds-1 from ethyl acetate extract of Cassia fistula stem bark with anti-diabetic property

Dr M Rajalakshmi
- Application No. : 2879/CHE/2012 Filed : 17-07-2012
Published : 17-07-2012 Granted

Scholarly Publications

Effect of hexane extract of Cassia fistula barks on blood glucose and lipid profile in Streptozotocin diabetic rats

Open Access
Journal Article
Year: 2008. Volume: 4 , Issue: 4 , Pages: 292-296 .
Authors: A. Nirmala; J. Eliza; M. Rajalakshm; Edel Priya; P. Daisy

Anti-diabetic properties of Tinospora cordifolia stem extracts on streptozotocin- induced diabetic rats

Journal Article
Year: 2009. Volume: 3 , Issue: 5 , Pages: 171-180 .

Synergistic Effects of Multifunctional Phytochemicals Modulating the Cellular Signal Pathways – as Neuroprotective Therapeutic Approach for Neurodegenerative Disorders

Book Chapter
Year: 2024. Pages: 97-123 .
Authors: Rajalakshmi Manikkam; Indu Sabapathy; Vijayalakshmi Periyasamy

Customised Microbiome Restoration Approaches in Older People: Perspectives and Therapeutic Prospects

Book Chapter
Year: 2024. Pages: 209-225 .
Authors: Rajalakshmi Manikkam; Vijayalakshmi Periyasamy; Indu Sabapathy

Repurposing of phytocompounds-derived novel bioactive compounds possessing promising anticancer and cancer therapeutic efficacy through molecular docking, MD simulation, and drug-likeness/ADMET studies

Book Chapter
Year: 2023. Pages: 201-222 .
Authors: Rajalakshmi Manikkam; Vijayalakshmi Periyasamy; Indu Sabapathy

Triterpenoids from Cassia fistula L. regulate p53 & ERK2 genes to induce apoptosis in HT-29 colon cancer cells

Journal Article
Authors: Rajini M. Kumar; Jeyapriyadharshini S; Anita Roy A; Ludas Antony; Indu S; Rajalakshmi Manikkam

Octyl gallate and gallic acid isolated from Terminalia bellarica regulates normal cell cycle in human breast cancer cell lines

Journal Article
Biomedicine & Pharmacotherapy. Year: 2018. Volume: 103 , Pages: 1577-1584 .
Authors: Mary Selesty Sales; Anita Roy; Ludas Antony; Sakhila K. Banu; Selvaraj Jeyaraman; Rajalakshmi Manikkam

Inhibition of cell survival and proliferation by nimbolide in human androgen-independent prostate cancer (PC-3) cells: involvement of the PI3K/Akt pathway

Journal Article
Molecular and Cellular Biochemistry. Year: 2017. Volume: 427 , Issue: 1-2 , Pages: 69-79 .
Authors: Paulraj Raja Singh; Elayapillai Sugantha Priya; Solaimuthu Balakrishnan; Ramachandran Arunkumar; Govindaraj Sharmila; Manikkam Rajalakshmi; Jagadeesan Arunakaran
Showing 1 to 8 of 40 publications