Ministry of Education
Sam Mathew
VIDWAN ID: 430688

Dr Sam Mathew

Male Doctor of Philosophy
Professor
REGIONAL CENTRE FOR BIOTECHNOLOGY
Haryana
Expertise: Developmental Biology
ORCID 0000-0001-7908-6094 Scopus 33167796200 Google Scholar tMNymiEAAAAJ
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5 Publications
3 Projects
0 Scopus Citations
46 CrossRef
14 Years Total Experience
Publications
5 Total
Articles
5
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46 Citations
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Professional Recognition

Wellcome DBT Intermediate Fellowship
2013
Wellcome Trust DBT
Cover image of issue
2023
EMBO Molecular Medicine
Cover image of issue
2022
Journal of Cell Science
Cover image of issue
2019
Developmental Biology

Community & Membership

RCB Institutional Biosafety Committee
Member
Jan 2023
RCB Institutional Animal Ethics Committee
Member Secretary
Jan 2023
Indian Society for Developmental Biology
Member
Jan 2018

Personal Details

Doctor of Philosophy
2006
N/A
Master of Science
1998
Rani Durgavati Vishwavidyalaya, Jabalpur
Professor
Nov 2024 – Present
REGIONAL CENTRE FOR BIOTECHNOLOGY
Associate Professor
Sep 2012 – Nov 2024
REGIONAL CENTRE FOR BIOTECHNOLOGY
Biological Sciences
Developmental Biology

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Scholarly Work

The Role of Transducin-like Enhancer of Split 3 (TLE3) in Regulating Myogenesis File No : EMR/2016/005218/AS (Ver-1) Submitted By
Completed
Role: Principal Investigator Grant: EMR/2016/005218
Amount: ₹45.17 Lac
Duration: 2017 – 2021
The role of MET-CBL signaling in rhabdomyosarcoma
Completed
Agency: Department of Bio-Technology Role: Principal Investigator Grant: 6242-P63/RGCB/PMD/DBT/SMJM/2015
Amount: ₹24.54 Lac
Duration: 2015 – 2019
The role of developmental Myosin Heavy Chains in skeletal muscle development, regeneration, homeostasis and disease
Completed
Agency: Department of Bio-Technology Role: Principal Investigator Grant: IA/I/13/1/500872
Amount: ₹3.31 Crore
Duration: 2014 – 2020

INVESTIGATION OF REGULATORY MOLECULES INVOLVED IN MAMMALIAN SKELETAL MUSCLE DIFFERENTIATION

University Manipal University
Year 2020
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Drosophila as a model to study the role of human embryonic Myosin Heavy Chain associated congenital myopathies

University Regional Centre for Biotechnology
Year 2022
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REGULATION OF SKELETAL MUSCLE DIFFERENTIATION DURING DROSOPHILA AND MAMMALIAN MYOGENESIS

University Manipal University
Year 2022
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Characterization of the role of Myosin Heavy Chains (MyHCs) in Mammalian Skeletal Muscle Development and Disease

University Kalinga Institute of Industrial Technology
Year 2023
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Scholarly Publications

The skeletal muscle slow-myosin heavy chain regulates mammalian metabolic homeostasis through the NRF2 pathway

Journal Article
Science Advances. Year: 2026. Volume: 12 , Issue: 23 , Pages: eaed2478 .
Authors: Sam J Mathew; Aparna Rai; Jaydeep Sharma; Somnath Mondal; Anushree Bharadwaj; Mahima Kumari
DOI 10.1126/sciadv.aed2478 Crossref Crossref: 1

Myosin heavy chain‐perinatal regulates skeletal muscle differentiation, oxidative phenotype and regeneration

Journal Article
THE FEBS JOURNAL (ELECTRONIC). Year: 2024. Volume: 291 , Issue: 13 , Pages: 2836-2848 .
Authors: Akashi Sharma; Aatifa Zehra; Sam J. Mathew
DOI 10.1111/febs.17085 Crossref Crossref: 8

The Wnt-pathway corepressor TLE3 interacts with the histone methyltransferase KMT1A to inhibit differentiation in Rhabdomyosarcoma

Journal Article
Oncogene. Year: 2024. Volume: 43 , Issue: 7 , Pages: 524-538 .
Authors: Bhargab Kalita; Subhashni Sahu; Anushree Bharadwaj; Lakshmikanthan Panneerselvam; Gerard Martinez-Cebrian; Megha Agarwal; Sam J. Mathew
DOI 10.1038/s41388-023-02911-3 Crossref Crossref: 6

Musculoskeletal defects associated with myosin heavy chain‐embryonic loss of function are mediated by the YAP signaling pathway

Open Access
Journal Article
EMBO Molecular Medicine. Year: 2023. Volume: 15 , Issue: 9 , Pages: EMMM202217187 .
Authors: Anushree Bharadwaj; Jaydeep Sharma; Jagriti Singh; Mahima Kumari; Tanushri Dargar; Bhargab Kalita; Sam J Mathew
DOI 10.15252/emmm.202217187 Crossref Crossref: 13

Myosin heavy chain mutations that cause Freeman-Sheldon syndrome lead to muscle structural and functional defects in Drosophila

Open Access
Journal Article
Developmental Biology. Year: 2019. Volume: 449 , Issue: 2 , Pages: 90-98 .
Authors: Shreyasi Das; Pankaj Kumar; Aakanksha Verma; Tushar K. Maiti; Sam J. Mathew
DOI 10.1016/j.ydbio.2019.02.017 Crossref Crossref: 18