DESIGN, SYNTHESIS, IN SILICO STUDIES, AND PHARMACOLOGICAL EVALUATION OF 5-ARYL-4-(CHLOROACETYLAMINO)-3-MERCAPTO-1,2,4-TRIAZOLE DERIVATIVES AS ANTICONVULSANT AGENTS
Authors: Kodagahally T. Gunashree; Chikkappaiahnayaka Santhosh; Aishwarya Bharathi H. M; Krishna Ravi Singh; Prabitha Prabhakaran; Maralinganadoddi P. Sadashiva
Rational design, molecular docking, dynamic simulation, synthesis, PPAR-γ competitive binding and transcription analysis of novel glitazones
Rational Design, Synthesis, and In Vitro Neuroprotective Evaluation of Novel Glitazones for PGC-1α Activation via PPAR-γ: a New Therapeutic Strategy for Neurodegenerative Disorders
Authors: B.R. Prashantha Kumar; Ashwini Prem Kumar; Jincy A. Jose; P. Prabitha; S. Yuvaraj; Sandhya Chipurupalli; Victoria Jeyarani; Chennu Manisha; Sayani Banerjee; Jeyaram Bharathi Jeyabalan; Suresh Kumar Mohankumar; S.P. Dhanabal; Antony Justin
Two Rationally Identified Novel Glitazones Reversed the Behavioral Dysfunctions and Exhibited Neuroprotection Through Ameliorating Brain Cytokines and Oxy-Radicals in ICV-LPS Neuroinflammatory Rat Model
Authors: Antony Justin; Premkumar Ashwini; Jincy A. Jose; Victoria Jeyarani; S. P. Dhanabal; Chennu Manisha; Subhankar P. Mandal; Guru Bhavimani; P. Prabitha; S. Yuvaraj; B. R. Prashantha Kumar