Rajesh Gokhale
VIDWAN ID: 275708

Prof Rajesh Gokhale

Male Doctor of Philosophy
Professor | Biology
Indian Institute of Science Education & Research (IISER), Pune,
Maharashtra
Expertise: Biology
103 Publications
0 Projects
5996 Scopus Citations
5882 CrossRef
5 Years 3 Months Total Experience
Publications
103 Total
Articles
99
Chapters
4
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Scopus Scopus
5,996 Citations
43 h-index
CrossRef CrossRef
5,882 Citations
42 h-index
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Personal Details

Doctor of Philosophy
Indian Institute of Technology, Delhi
Master of Science
Indian Institute of Technology, Hyderabad
Professor
Jun 2021 – Present
Indian Institute of Science Education & Research (IISER), Pune, | Biology
Biological Sciences
Biology

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Scholarly Publications

Covalent reinforcement of a fragile region in the dimeric enzyme thymidylate synthase stabilizes the protein against chaotrope-induced unfolding

Journal Article
Biochemistry. Year: 1996. Volume: 35 , Issue: 22 , Pages: 7150-7158 .
Authors: Rajesh S. Gokhale; Sanjay Agarwalla; Daniel V. Santi; Padmanabhan Balaram

Covalent tethering of the dimer interface annuls aggregation in thymidylate synthase

Journal Article
PROTEIN SCIENCE (ELECTRONIC). Year: 1996. Volume: 5 , Issue: 2 , Pages: 270-277 .
Authors: Sanjay Agarwalla; Rajesh S. Gokhale; P. Balaram; Daniel V. Santi

Thermal stabilization of thymidylate synthase by engineering two disulfide bridges across the dimer interface

Journal Article
Journal of Molecular Biology. Year: 1994. Volume: 235 , Issue: 1 , Pages: 89-94 .
Authors: Rajesh S. Gokhale; Sanjay Agarwalla; V.S. Francis; Daniel V. Santi; P. Balaram

Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride: Evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant

Journal Article
Biochemistry. Year: 1999. Volume: 38 , Issue: 1 , Pages: 423-431 .
Authors: Rajesh S. Gokhale; Soumya S. Ray; Hemalatha Balaram; P. Balaram

Cavity-creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: Restoration of stability by disulfide cross- linking of subunits

Journal Article
Biochemistry. Year: 1999. Volume: 38 , Issue: 1 , Pages: 478-486 .
Authors: B. Gopal; Soumya S. Ray; R. S. Gokhale; H. Balaram; M. R. N. Murthy; P. Balaram

Triosephosphate isomerase from Plasmodium falciparum: The crystal structure provides insights into antimalarial drug design

Open Access
Journal Article
Structure. Year: 1997. Volume: 5 , Issue: 6 , Pages: 751-761 .
Authors: Sameer S Velanker; Soumya S Ray; Rajesh S Gokhale; Suma S; Hemalatha Balaram; P Balaram; MRN Murthy

Disulfide engineering at the dimer interface of Lactobacillus casei thymidylate synthase: Crystal structure of the T155C/E188C/C244T mutant

Open Access
Journal Article
PROTEIN SCIENCE (ELECTRONIC). Year: 1999. Volume: 8 , Issue: 4 , Pages: 930-933 .
Authors: S.S. Velanker; R.S. Gokhale; Soumya S. Ray; B. Gopal; S. Parthasarathy; D.V. Santi; P. Balaram; M.R.N. Murthy

Retrobiosynthetic approach delineates the biosynthetic pathway and the structure of the acyl chain of mycobacterial glycopeptidolipids

Open Access
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY. Year: 2012. Volume: 287 , Issue: 36 , Pages: 30677-30687 .
Authors: Vats, A.; Singh, A.K.; Mukherjee, R.; Chopra, T.; Ravindran, M.S.; Mohanty, D.; Chatterji, D.; Reyrat, J.-M.; Gokhale, R.S.
Showing 1 to 8 of 103 publications