Antiproliferative activity of the isoindigo 5′-Br in HL-60 cells is mediated by apoptosis, dysregulation of mitochondrial functions and arresting cell cycle at G0/G1 phase
Authors: Aziz, M.A.; Periyasamy, S.; Al Yousef, Z.; AlAbdulkarim, I.; Al Otaibi, M.; AlFahed, A.; Alasiri, G.
The anticancer activity of the substituted pyridone-annelated isoindigo (5'-Cl) involves G0/G1 cell cycle arrest and inactivation of CDKs in the promyelocytic leukemia cell line HL-60