Concomitant high oxidative stress and poor antioxidant enzyme activity with DNA damage may underlie obesity and reduced longevity in WNIN/Ob obese rats
Increased stress and altered expression of histone modifying enzymes in brain are associated with aberrant behaviour in vitamin B12 deficient female mice
SIRT1 promotes neuronal fortification in neurodegenerative diseases through attenuation of pathological hallmarks and enhancement of cellular lifespan.